Composition:

Active ingredient: domperidone; 1 tablet contains 10 mg of domperidone; excipients: lactose monohydrate; pregelatinized starch; croscarmellose sodium; microcrystalline cellulose; sodium lauryl sulfate; povidone; magnesium stearate; coating: Opadry II White film-coating mixture (hypromellose (hydroxypropyl methylcellulose); lactose monohydrate; polyethylene glycol; titanium dioxide (E 171); triacetin).

Directions for use:

To relieve symptoms of nausea and vomiting. Adults and children 12 years of age and older weighing at least 35 kg: 1 tablet (10 mg) 3 times daily. The maximum daily dose is 3 tablets (30 mg per day). It is recommended to take Motrix before meals. Absorption of the medication is slightly delayed if taken after a meal. The duration of treatment should not exceed 1 week.

Adults over 60 years of age. Patients aged 60 years and older should consult a doctor before taking this medication.

Renal impairment. Since the half-life of domperidone is prolonged in patients with severe renal impairment (serum creatinine > 6 mg/100 mL, i.e., > 0.6 mmol/L), the frequency of administration of Motrix should be reduced to once or twice daily, depending on the severity of the impairment; it may also be necessary to reduce the dose.

Hepatic impairment. Motrix is contraindicated in patients with moderate (7–9 points on the Child–Pugh scale) or severe (˃ 9 points on the Child–Pugh scale) hepatic impairment. No dose adjustment is required for patients with mild hepatic impairment (5–6 points on the Child–Pugh scale).

Children. This medication is indicated for the treatment of children aged 12 years and older with a body weight of at least 35 kg. Domperidone should be administered to children at the lowest effective dose for the shortest possible duration.

Adverse reactions:

Immune system: frequency unknown—allergic reactions, including anaphylaxis, anaphylactic shock, and hypersensitivity. Endocrine system: rare—increased prolactin levels. Psychiatric disorders: uncommon—decreased or absent libido, irritability, agitation, nervousness; very rare—depression, anxiety.

Manufacturer:

JSC “KYIV VITAMIN PLANT,” 38 Kopylivska St., Kyiv, 04073, Ukraine. https://www.vitamin.com.ua

Motoryks

30 таблеток

Indications for use:

To relieve symptoms of nausea and vomiting.

Contraindications:

– patients with a known hypersensitivity to the drug or its excipients;

– patients with a prolactin-secreting pituitary tumor (prolactinoma);

– patients with severe or moderate hepatic and/or renal impairment (see sections “Special Considerations for Use” and “Pharmacokinetic Properties”);

– patients with known prolongation of cardiac conduction intervals, particularly the QTc interval; patients with significant electrolyte imbalances or underlying heart conditions, such as congestive heart failure (see the “Special Considerations for Use” section);

– patients with hepatic insufficiency;

– if stimulation of gastric motility may be dangerous, for example, in cases of gastrointestinal bleeding, mechanical obstruction, or perforation;

– concomitant use of ketoconazole, erythromycin, or other potent CYP3A4 inhibitors is contraindicated;

– Concomitant use of medications that prolong the QT interval, such as fluconazole, erythromycin, itraconazole, oral ketoconazole, posaconazole, ritonavir, saquinavir, telaprevir, voriconazole, clarithromycin, amiodarone, and telithromycin (see the sections “Special Considerations for Use” and “Drug Interactions and Other Interactions”).

Before using the medication “Motrix,” please read the full text of the current prescribing information.

Where to buy:

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